MOUSE ANTI SLP-76 MBS212748 from MyBioSource.com

Description

MBS212748 recognises the SH2 domain-containing leucocyte protein (SLP-76), a 76kDa tyrosine phosphoprotein, expressed primarily by T lymphocytes and cells of the myeloid lineage. SLP-76 is one of several adaptor proteins assisting with TCR-mediated signal transduction, through GRB2 binding, functioning as a substrate for the protein-tyrosine kinase ZAP-70 and thus playing a crucial role in both T cell ontogeny and activation. Other molecules that associate with SLP-76 include phospholipase C (PLC) -gamma, Vav, Nck and fyn binding protein

Product Specs
ItemMOUSE ANTI SLP-76
CompanyMyBioSource.com
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberMBS212748
Quantity0.1 mg
ApplicationsImmunoprecipitation (IP), Western Blot (WB)
ConcentrationIg concentration 1.0 mg/ml
Conjugate/TagUnconjugated
FormatPurified
Purified IgG - liquid
ReactivityMouse, Pig
TargetSLP-76
IsotypeIgG2b
Molecular Weight60,188 Da
CloneSLP-76/03
HostMouse
ImmunogenThis item recognises the SH2 domain-containing leucocyte protein (SLP-76), a 76kDa tyrosine phosphoprotein, expressed primarily by T lymphocytes and cells of the myeloid lineage.

SLP-76 is one of several adaptor proteins assisting with TCR-mediated signal transduction, through GRB2 binding, functioning as a substrate for the protein-tyrosine kinase ZAP-70 and thus playing a crucial role in both T cell ontogeny and activation. Other molecules that associate with SLP-76 include phospholipase C (PLC)-gamma, Vav, Nck and fyn binding protein
NCBI Full Gene Namelymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
NCBI Gene AliasesSLP-76, SLP76
ClonalityMonoclonal